@Tyvey I think anything that directly interacts with your neurotransmitters, well in the way pheromones do at least, should not be combined with excessive amounts of inhibition lowering chemicals. Also, if nothing else, drinking may cause the dreaded neurotransmitter burn-out to occur more rapidly. Which in effect may hasten a tolerance to one's favorite blend. I haven't experienced this personally, so this is purely conjecture on my part. I have experienced the major decrease in tolerance, with Heart & Soul having the most pronounced inhibition lowering results.